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What is Tasigna?

The generic name of Tasigna is Nilotinib Capsules. Tasigna is used to treat both chronics and accelerated Philadelphia Chromosome-Positive Myeloid Leukemia in adults that are resistant or intolerant to prior therapy, including imatinib. Tasigna is also recommended to treat adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in the chronic phase of the disease. Tasigna works by interfering with the growth and Spread of Cancer Cells in the body. Tasigna is used for adults and children who are at least 1 year old. At Discount Pharmacy Rhode Island you can get Tasigna medication by utilizing online services and get it delivered at your place across Bristol, RI.

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What is Tasigna Used For?

Tasigna is used for the treatment of Philadelphia chromosome-positive CML that is refractory or intolerant to prior therapy, including imatinib. Tasigna acts as chemical messengers and can Stimulate Cancer Cells to grow. Tasigna is usually given after other medications have been tried without success. Your Bristol, RI doctor may have prescribed Tasigna for the condition not mentioned here.

How To Use Tasigna?

Tasigna is a prescription medicine and must be used according to the recommendations of the Bristol, RI doctor. Take Tasigna by mouth on an empty stomach, usually twice daily. Do not eat any food for at least 2 hours before or for 1 hour after taking your dose. If you are also taking an antacid, take it 2 hours before or after Tasigna.

Why Tasigna is Prescribed?

Tasigna is prescribed to treat a certain Type of Blood Cancer (chronic myelogenous leukemia-CML). Tasigna is used in Bristol, RI adults with newly diagnosed Ph+ CML in the chronic phase (typically considered the first stage of CML), or Ph+ CML in either the chronic phase or the accelerated phase (a stage of CML where you have more symptoms of leukemia).

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What Conditions Does Tasigna Treat?

Tasigna is used to treat adults and children with either of the following:

  • Newly diagnosed Ph+ CML in the chronic phase (typically considered the first stage of CML), or
  • Ph+ CML in the chronic phase that’s been treated in the past with a tyrosine kinase inhibitor (TKI).
  • It can also be used in adults during the accelerated phase (when the cancer cells are dividing rapidly and the patient may have more symptoms).

Tasigna Dosage

For Ph+ CML in adults who are newly diagnosed

  • The usual dosage of Tasigna for adults with newly diagnosed Ph+ CML that hasn’t been treated in the past is 300 mg twice daily
  • The usual dosage for adults with Ph+ CML who didn’t improve with or couldn’t tolerate certain past treatments is 400 mg twice daily.

For Ph+ CML in children

  • The usual dose of Tasigna for children with Ph+ CML is 230 mg of drug per square meter of their body surface area (mg/m2). This dose should be taken twice daily.

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Side Effects of Tasigna:

Common side effects include but are not limited to:

  • Skin Rash
  • Itching
  • Headache
  • Nausea
  • Fatigue
  • Tiredness
  • Joint or Muscle Aches or Pain
  • Back Pain
  • Diarrhea
  • Constipation
  • Temporary Hair Loss, or
  • Cold Symptoms (Stuffy Nose, Sneezing, Cough, or Sore Throat)
  • Severe Stomach or Abdominal Pain
  • Toe or Joint Pain
  • Painful Urination
  • A Change in The Amount of Urine
  • Swelling Hands/Ankles/Feet
  • Unusual or Rapid Weight Gain
  • Symptoms of High Blood Sugar (Such As Increased Thirst or Urination), or
  • Signs of Liver Disease

Cautions To Take Tasigna:

You should not use Tasigna if you are allergic to it or any of its ingredients. You should not use Tasigna if you have:

  • Low blood levels of potassium or magnesium; or
  • A heart rhythm disorder called long QT syndrome
  • Heart disease, heartbeat problems, or long QT syndrome (in you or a family member)
  • A stroke
  • Blood circulation problems in your legs
  • Bleeding problems
  • Low blood levels of potassium or magnesium
  • Severe problems with lactose (milk sugar)
  • Liver disease
  • Pancreatitis; or
  • Surgical removal of your stomach (total gastrectomy)
  • Do not use Tasigna if you are pregnant

Inform your doctor if you are breastfeeding

Frequently Asked Questions

1. What if I miss a dose?

If you miss a dose of Tasigna, just skip the missed dose. Then take your next scheduled dose at the usual time. Don’t take more than one dose to make up for the missed dose. Taking more than one dose at a time will increase your risk of serious side effects.

2. Will I need to use Tasigna long term?

Tasigna is meant to be used as a long-term treatment. If you and your doctor determine that Tasigna is safe and effective for you, you’ll likely take it long term.

3. Is Tasigna a chemotherapy drug?

No, Tasigna is not considered a chemotherapy drug. The term “chemotherapy” is often used to describe traditional drugs that treat cancer.

4. How long does it take to work?

Tasigna begins working shortly after you take your first dose. However, you may not notice that Tasigna is working to make you feel better until you’ve had treatment for several months.

5. What should I avoid while using Tasigna?

Avoid the use of grapefruit products while taking Tasigna.

  • Avoid taking a stomach acid reducer (such as Pepcid, Tagamet, or Zantac) within 10 hours before or 2 hours after you take Tasigna.
  • Avoid taking an antacid that contains aluminum, magnesium, or simethicone

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